Yes.. it is called the "binding defect"
In essence this is the very reason you are
able to pick locks.
If the pins were all straight and you turned the plug then all the pins would touch the shell of the lock at the same time and picking would be imposible...
However locks do not have the holes drilled exactly straight, and because of this when you begin to turn the plug clockwise the pin which is in the hole that has drifted most towards the right hand side will get trapped between the plug and the cylinder.. since one pin as touched first you need to lift it.. now you lift it untill the bottom pin reaches the top of the plug - the top pin will now go into the cylinder and the bottom pin will fall back down, and the plug will move slightly so that it stops the top pin from falling down... Normaly the spring would push down onto the top pin and then the top pin pushes down and rests on the bottom pin, but when the top pin is stuck inside the cylinder it is no longer able to enter the plug and therefor it cannot exert preassure upon the bottom pin.... This is how you can tell if you've set a pin because the spring preassure will dissapear and it will be very easy to lift up.
Now presume that the holes have been drilled slightly diagonaly towards the right - when you turn the plug the last pin will bind, and you follow the procedure I stated above, then when that top-pin has been set the plug will turn a bit... and it will be stopped by touching another pin.. this pin needs to be set.. then it sets on another. Once all of the top pins are in the cylinder the plug will turn freely ad you wil have successfully 'picked' it.
Of course, depending upon how the holes are drilled different pins bind in different orders in each lock - so it is as much a skill in finding the pin which binds most as it is a skill to lift the pins to the right height.
the pin which is binding is stopping the plug from turning and it will be the one that is hardest to lift up.. the one which offers the most resistance.
It is simple in theory and I'm sure you may walk away now and feel you will be able to pick a lock, but it is a skill... to find the pin which is binding is neither simple nor obvious untill you try to do it... and furthermore knowing when you are using too much tension and making the pins set wrongly... it is something you will learn - of this I have no doubt, but it is something which you need to work upon...
Buy a lock you can take apart, and then follow my guide to take it apart, then follow digital_blue's guide he wrote for ways to practice.
Practice - it is the single thing that picking locks consists of.. get to know how it works, get to know how the pins set, which order they bind in...
It's nothing magic... just a simple defect in the lock and skill on your behalf... exploit this defect and you'll be like a ninja.
All this potential requires practice... you are UNLOCKING your skills
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that is one long post.... but hopefuly somebody will read this and make use of it.
illusion