Security through Obscurity almost sounds good in theory (Until you actually think about it) but doesn't work in practice. When you design your own lock you may easily overlook things that others might not. Take this entire thread as an example. Someone might try something that you never thought of and bypass your lock or it may be vulnerable in ways you could never imagine on your own. Many heads are better than one! Especially many heads experienced in manipulation and bypass!

Make it public and open to criticism and you will eventually come out with a better design.
(Think Open Source, but with lock hardware!)
If you want a real working security concept, think
"Security through Diversity!" Get yourself a couple (or many) different types/brands of lock that require different tools and skill to manipulate. Then hide/obscure them if you wish!

Make sure they are as different as possible. A disc lock, a pin tumbler, a tubular, a combo, etc... How many people here can do it all, quickly? Make 'em need to carry more tools as well. At the very least this should annoy the heck out of someone trying to get in and may make them move on to somewhere else...
The more secure you get, the less convenient. It's a trade-off, so make yourself a good comprimise. All those locks do no good if you leave them unlocked just because they become inconvenient. Some people are better off with one good lock.... ....but two of different types is not that much less convenient and increases security a bit. It could be worth it!
Putting in a decoy lock, aka kwikset (along with your hidden higher security locks) and a (Hidden) security camera to catch people in the act might be a good idea too! Knowing who is trying could be invaluable! (And don't forget to secure windows and other points of entry!) 2 security cams with one being hidden and the other a decoy might be a good idea as well!

Put the real one far enough away to make it hard to find just in case. Maybe in a parked car in front of your house for instance and you might catch someone trying to steal your car as well!

(Remote recorder would be very useful so you get to keep a tape of the guy vandalizing or stealing the camera!) Just a thought...
Make things hard to get into, but not flashy. If you are really concerned about security than you probably don't want to make your place look interesting. Make it look like just another house on the block. Remember, most thieves probably won't be attempting to pick, so make sure things can resist brute force as well as look normal for your area. Beef things up in a way that doesn't draw attention. (This includes windows, etc...)
Unfortunately, none of this prevents someone from vandalizing your locks but you might catch them in the act, however. (and maybe have some proof so law enforcement will believe you.)

Catching the culprit is almost as important as not getting broken into in the first place for obvious reasons.
...And keeping your real keys secured in some way at all times, having a set of decoy keys out in the open on a keyhook or something could prove to be an eye opening experience when you find the decoys missing! Mark your keys and other property in some rememberable yet subtle way for easy identification in the future.
Wow this is gettin way too long...
Anyway, just remember that Obscuring things doesn't make them secure. A hidden kwikset is still a kwikset, but a hidden Medeco is still hard to manipulate!